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Clinical Trials/TCTR20190811001
TCTR20190811001
Not yet recruiting
Phase 2

Early detection of dementia using brain perfusion SPECT with cognitive stress test

Ratchadapiseksompotch Grant, Chulalongkorn University0 sites155 target enrollmentAugust 11, 2019
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Conditionsmild cognitive impairment (MCI)mild cognitive impairmentearly detectiondementia screeningbrain imagingcognitive stressperfusion SPECT

Overview

Phase
Phase 2
Intervention
Not specified
Conditions
mild cognitive impairment (MCI)
Sponsor
Ratchadapiseksompotch Grant, Chulalongkorn University
Enrollment
155
Status
Not yet recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
August 11, 2019
End Date
August 31, 2024
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Ratchadapiseksompotch Grant, Chulalongkorn University

Eligibility Criteria

Inclusion Criteria

  • •\- Age 55 \- 85 years
  • •\- No known history of uncontrolled psychiatric disease
  • •\- Stable controllable dementia without choline esterase inhibitor adjustment in the past 3 months
  • •\- Thai nationality

Exclusion Criteria

  • •\- Diseases which affect this study eg.chronic kidney disease (GFR\<30 ml/min), chrnic liver disease (Child\-Pugh class B), DM (HbA1c\>\=7mg% ), all types of cancer
  • •\- Who cannot perform CT or MRI of the brain
  • •\- Those who have dementia etiology from other causes eg. depression, cerebrovascular disease, etc.
  • •\- Patients with neurological disease that affects cognition eg. epilepsy, parkinson disease etc.
  • •\- Those who cannot read/write/speak Thai language.
  • •\- Those who have MRI finding of frank cerebrovascular disease
  • •\- Those who have abnormal lab tests: CBC, Bun, Cr, Electrolytes, LFT, metabolic blood test (Thyroid Function Test, folate, B12, lipid profile, FBS, HbA1c), inflammation/infection blood tests (Syphilis, HIV, ESR)
  • •\- Mild dementia patients with abnormal special blood test (autoimmune/paraneoplastic panel, antineuronal IgG, anti\-TPO, anti\-thyroglobulin)

Outcomes

Primary Outcomes

Not specified

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