IRCT20150606022562N5
Recruiting
Phase 3
Evaluation of the effect of melatonin supplementation on Insulin metabolism markers, parameters of oxidative stress and gene expression of PPAR-? & ox-LDL in patients with diabetic nephropathy
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Kashan University of Medical Sciences
- Enrollment
- 60
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •GFR 15 to 89 ml per minute
- •Moderate blood pressure (systolic pressure 140\-160 and diastolic pressure 80\-100 mmHg)
- •No specific cardiovascular disease, cancer, inflammatory diseases, autoimmune and hyper or hypothyroidism
- •Non\-presence of urinary tract infection and other factors of proteinuria
Exclusion Criteria
- •Special illness that leads to hospitalization.
- •High blood pressure (systolic pressure upper than 160 and diastolic pressure upper than 100 mmHg)
- •Unwillingness to cooperate
- •Taking fluvoxamine and any antioxidant supplement
- •Working at night shifts
- •Smoking and alcohol consumption
- •Breastfeeding and pregnancy
Outcomes
Primary Outcomes
Not specified
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