ung Strain and Mortality in Acute Respiratory Distress Syndrome

Completed

• Conditions: Acute Respiratory Distress Syndrome; Lung strain; End-expiratory lung volume; Mortality

• Registration Number: TCTR20220418004
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-12-31
• Study Start: 2022-04-18
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

1. ARDS according to BERLIN definition 2012
2. Patients had lung volume measurement by nitrogen washout washin technique using Engstrom Carestattion ventilator
3. Age equal to or more than 18 years
4. Use PEEP of at least 5 cmH2O
5. Use FiO2 equal to or less than 0.6

Exclusion Criteria

1. Pneumothorax
2. Severe COPD
3. AutoPEEP
4. Lung bleb on CXR
5. Pregnancy
6. Lung volume measurement after diagnosis ARDS more than 96 hours

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ung strain between survival and non-survival ARDS patients At the begining of the study Tidal volume were measured by ventilator parameter and lung volume (EELV) were measured by nitrogen washout/washin technique using the module integrated into Engstrom Carestation ICU ventilators

Secondary Outcome Measures

Name	Time	Method
ung parameter between survival and non-survival ARDS patients At the begining of the study Ventilator parameter and arterial blood gas,Mortality, ICU length of stay, hospital length of stay, ventilator free day between high lung strain and low lung strain Until patient discharge from the hospital medical record