Cryoablation for Advanced Bone and Soft Tissue Tumors

Recruiting

• Conditions: Sarcoma; Cryoablation
• Interventions: Procedure: Cryoablation

• Registration Number: NCT05615545
• Lead Sponsor: Henan Cancer Hospital

Brief Summary

This is a single-center, open, retrospective clinical study of patients with metastatic/surgically unresectable bone and soft tissue sarcoma undergoing cryoablation of selected tumor lesions. All eligible patients were enrolled. Basic data and treatment methods of these patients were collected, and efficacy and safety were evaluated.

Detailed Description

This is a single-center, open, retrospective clinical study of patients with metastatic/surgically unresectable bone and soft tissue sarcoma undergoing cryoablation of selected tumor lesions. Clinical data of eligible patients were scheduled to be retrospectively collected from December 2016 to February 28, 2022. All patients eligible for inclusion. Basic data and treatment methods of these patients were collected, and efficacy and safety were evaluated.

Study Timeline

• Study Start: 2022-03-10
• Study First Submitted: 2022-11-07
• Study First Submitted QC: 2022-11-07
• Study First Posted: 2022-11-14
• Status Verified: 2023-11
• Last Update Submitted: 2024-02-05
• Last Update Posted: 2024-02-07
• Primary Completion: 2024-10-28
• Study Completion: 2024-10-28

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

No age restriction, male or female.

The pathological diagnosis was a subtype of bone and soft tissue sarcoma.

The clinical stage was determined to be metastatic or locally unresectable bone and soft tissue sarcoma.

At least one cryoablation of tumor lesions was performed in our hospital.

Target lesions can be evaluated according to the efficacy evaluation criteria for solid tumors (RECIST; Version 1.1) Measure diameter changes.

Follow-up data were complete.

Exclusion Criteria

Not applicable.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cryoablation	Cryoablation	Cryoablation of selected tumor lesions

Primary Outcome Measures

Name	Time	Method
Survival rates	12 months after surgery	1-year survival rate
There was no local recurrence survival rate	12 months after surgery	The 1-year survival rate without local recurrence

Trial Locations

Locations (1)

Department of Bone and Soft Tissue ,Henan Cancer Hospital; 🇨🇳 Zhengzhou, Henan, China