Study for electroacupuncture in the treatment of severe brain injury patients with acute gastrointestinal injury
- Conditions
- severe brain injury patients
- Registration Number
- ITMCTR2000003239
- Lead Sponsor
- The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- Not specified
1. All patients admitted to ICU of our hospital were diagnosed as brain injury (stroke, brain injury) by skull CT examination, with GCS score of 3-8 and AgI level II and above(the score of gastrointestinal functional injury refers to the AGI diagnostic criteria developed by the European society of critical care medicine (ESICM));
2. Aged >=18 years old;
3. The family members of the patients agreed to participate in the study.
1. Severe trauma of chest and abdomen;
2. gastrointestinal motility drugs were used before admission;
3. local skin injuries at Zusanli, Zhongwan, Tianshu, Shangjuxu, xiajuxu, Zhongwan and other acupoints were not suitable for Electroacupuncture;
4. routine blood platelet count < 50*10^9/L or severe coagulation dysfunction (INR > 2.0);
5. severe primary gastrointestinal diseases (such as massive alimentary tract bleeding, mechanical intestinal obstruction and intestinal perforation);
6. hemodynamic instability and shock were not controlled 24 hours after admission to ICU;
7. brain death.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 28-day mortality;
- Secondary Outcome Measures
Name Time Method bowel sounds;diamine oxidase;gastrointestinal function score;gastrin;Incidence of hospital acquired pneumonia;APACHE? score;duration of ICU stay;D-lac;duration of mechanical ventilation;intra-abdominal pressure;abdominal circumference;lipopolysaccharides;motilin;Multiple Organ Dysfunction Syndrome score;Sequential Organ Failure Assessment score;