Amount of propofol required to produce anaesthesia when given with fentanyl or dexmedetomidine with exclusive intravenous drugs
Phase 4
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/11/047007
- Lead Sponsor
- ady Hardinge Medical College
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA I and II
Exclusion Criteria
1.Laparoscopic surgery with an anaesthetic duration of >3hours.
2.Any known allergy to drugs used in the study.
3.BMI > 35.
4.Known psychiatric illness.
5.Addiction to drugs and alcohol.
6.Chronic opioid therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean/ Median effect site concentration (EC50) of propofol with fentanyl or dexmeditomidine will be compared by using Studentâ??s t test/ Mann Whitney U test.Timepoint: At the end of anaesthesia
- Secondary Outcome Measures
Name Time Method 1 Number of patients having side effects <br/ ><br>2 Mean time to achieve modified aldrete score more than equal to 9 <br/ ><br>3 Number of patients having post operative nausea vomitting <br/ ><br>4 Mean analgesic requirement in post operative periodTimepoint: 1 After stopping total intravenous infusion <br/ ><br>2 After stopping total intravenous infusion <br/ ><br>3 First 24 hours post operative period <br/ ><br>4 First 24 hours post operative period