on-surgical treatments for disease of the gum surrounding dental implants

Not Applicable

• Conditions: Peri-implantitis at a dental implant; Oral Health

• Registration Number: ISRCTN13724605
• Lead Sponsor: Clinica Merli

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/32678954/ (added 15/03/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-09-18
• Last Update Posted: 30 March 2021
• Study Completion: 2021-07-05

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

1. Aged 18 or older
2. Suffering from initial to moderate peri-implantitis at an implant site
3. Presence of at least one screw-type titanium implant exhibiting signs of moderate peri-implantitis: maximum probing depth from 5 to 8 mm bleeding on probing or suppuration in at least one site, and radiographic bone loss in at least one site
4. Radiographic infraosseous component of the defect = 5mm
5. Radiographic suprabony component of the defect = 4mm
6. Presence of at least 2 mm of keratinized mucosa
7. Implant loading of at least 6 months

Exclusion Criteria

1. Patients incapable of giving informed consent
2. Mobile implant
3. Head and neck irradiated patient
4. Chemo or immunosuppressive therapy over the previous 5 years
5. Treatment with intravenous amino-bisphosphonates
6. Poor oral hygiene and motivation
7. Untreated periodontitis
8. Uncontrolled diabetes
9. Pregnancy and lactating period
10. Substance abusers
11. Allergy to chlorhexidine or phenolic or sulfur compounds
12. Smoking more than 20 cigarettes per day, or the equivalent
13. Patients unable to attend the 3-year follow-up

Study & Design

• Study Type: Interventional
• Study Design: Not specified