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临床试验/CTRI/2021/06/034181
CTRI/2021/06/034181已完成未知

Comparison of Efficacy of IV Esmolol VS IV Dexmedetomidine inAttenuation of Sympathomimetic response to Laryngoscopy andIntubation in Patients undergoing Elective Major Surgeries.A prospective, double-blind, randomized controlled study.

Dr Arundhati Chadha0 个研究点目标入组 56 人开始时间: 待定最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
56

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • Patients undergoing Elective Major surgeries,
  • Patient related factors,
  • 1. Adults between 30 to 65 yrs.
  • 2. BMI between 18.5 to 30 kg per m2 .
  • 3. Mallampati Airway class I and II.
  • 4. ASA I, II and III patients.
  • Surgery related factors,
  • 1. Operative time more than 4 hours.
  • 2. Expected Excessive intra operative blood loss.
  • 3. Expected peri operative blood transfusion of more than or equal to 2 PRBC.
  • 4. And, or one of the following surgeries,
  • i. Radical hysterectomy.
  • iii. Discectomy, Laminectomy.
  • iv. Thyroidectomy.
  • v. lung operations.
  • vi. Ileostomy, colectomy.
  • vii. Neck lymph node dissection.
  • viii. Neurosurgeries.
  • ix. Heart surgeries.

排除标准

  • 1. Unwillingness to give consent.
  • 2. Allergy to any of the drugs.
  • 3. Anticipated Difficult Airway.
  • 4. Intubation attempts lasting for more than 30 secs.
  • 5. Left ventricular ejection fraction less than 45 percent.
  • 6. Pregnant and lactating females.
  • 7. Acute or Chronic Renal Disease.
  • 8. Acute or Chronic Liver Disease.
  • 9. Chronic Obstructive Pulmonary Disease.
  • 10. ASA IV, V and VI patients.

研究者

发起方
Dr Arundhati Chadha

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