ACE inhibition in Fontan patients: its effect on body fluid regulation.

Phase 4

Completed

• Conditions: 10010394; Fontan circulation; one chamber heart; 10007510

• Registration Number: NL-OMON46953
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-12-17
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 71

Inclusion Criteria

Fontan patiënts
Patiënts from 8 until 18 years old

Exclusion Criteria

Fontan patients who already use enalapril

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Cardiopulmonary exercise stress test: VO2peak (maximal oxygen consumption)<br /><br>- Cardiac autonomic nervous activity: heart rate variability and pre-ejection<br /><br>period.<br /><br>- Outcome of passive leg raising and head up tilt table testing: cardiac output<br /><br>and cardiac autonomic tone.</p><br>