NCT02173613TerminatedNot Applicable
Reduction of the Duration of Antibiotic Guided by Procalcitonin in Infections Lungs of Hospitalized Elderly: a Randomized
University Hospital, Grenoble2 sites in 1 country117 target enrollmentStarted: August 1, 2012Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Sponsor
- Enrollment
- 117
- Locations
- 2
- Primary Endpoint
- Duration of antibiotic therapy
Study Overview
Brief Summary
The main objective is to evaluate the interest of the repeated measurement of procalcitonin in patients with pulmonary infection to reduce the duration of antibiotic therapy in comparison with a conventional clinical strategy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Other
- Masking
- None
Eligibility Criteria
- Ages
- 80 Years to — (Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age ≥ 80 years
- •Started antibiotics for a chest infection
- •Procalcitonin performed J0 antibiotic treatment
- •Person affiliated to the social security
Exclusion Criteria
- •Patients with a documented infection with germs after Listeria spp, Legionella pneumophilia, Mycobacterium tuberculosis
- •Patients with a documented infection with a virus or parasite (eg hemorrhagic fever, malaria)
- •Patients with endovascular infection associated (endocarditis, pacemaker. Intravascular catheter)
- •Patients with lung abscess associated upon entry Patients with a chronic infection associated
- •Patients with severe immunosuppression (HIV or transplant)
- •Palliative patient
- •Death within 24 hours of admission to nursing units.
- •Presence of antibiotic treatment for chronic infection.
- •Patient under guardianship, curatorship or any other administrative or judicial action or deprivation of the right or freedom
- •Patients hospitalized without their consent
Outcomes
Primary Outcomes
Duration of antibiotic therapy
Time Frame: Success of antibiotic therapy within 45 days of inclusion
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (2)
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