Detecting and Quantifying Sulci and White Matter in Fetus' Brain Along the Third Stage of Gestation
试验速览
- 阶段
- 不适用
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- morphological changes of the developing fetal brain
研究概览
简要总结
Gyrogenesis is an ontogenic process that transforms the smooth (lissencephalic) cortex toward its mature, convolved (gyrencephalic) state. A tortuous, branching and deepening pattern of sulci and fissures outlines for a well-developed cortex.
The aim of this study is to find an algorithm that can detect the sulci in ultrasound images of fetus' brain and measure the length of it. This algorithm can be used for research demands like learning the development of the brain from embryo stages until the birth of the baby
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant women between the ages of 18-35
- •Gestational age between 25-40 weeks
- •Low risk pregnancies
排除标准
- •Multiple gestation
- •Fetal brain abnormality
结局指标
主要结局
morphological changes of the developing fetal brain
时间窗: 9 months
Ultrasound measurements of the fetal brain sulcation by a computerized algorithm
次要结局
未报告次要终点
研究者
Yuval Ginsberg, MD
Principal investigator
Rambam Health Care Campus
