Comparison of two protocol chemotherapy for cisplati

Phase 3

• Conditions: C00-C14; epithelial carcinoma of head and neck.; Malignant neoplasms of lip, oral cavity and pharynx

• Registration Number: IRCT20180223038829N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

histologically proven malignancy in resected specimen
all epithelial carcinoma of head and neck that needs concurrent chemoraradiation
stages 3,4 of the disease
aged 20-75 years old
ECOG Performance Status :0-2
no prior radiation therapy or chemotherapy
adequate organ function
written informed consent

Exclusion Criteria

active multiple primary cancers; synchronous or metachronous within 5 years
infection requiring systemic treatment
women who are or may be pregnant
psychosis or psychiatric symptoms/signs that judged to male participation in the study difficult
uncontrolled diabetes mellitus
uncontrolled hypertension

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ymphocyte. Timepoint: weekly. Method of measurement: blood serum level.;Neutrophil. Timepoint: weekly. Method of measurement: blood serum level.;Hemoglobin. Timepoint: weekly. Method of measurement: blood serum level.;Platelet. Timepoint: weekly. Method of measurement: blood serum level.;Creatinin. Timepoint: weekly. Method of measurement: blood serum level.;Leukocyte. Timepoint: weekly. Method of measurement: blood serum level.