NL-OMON27218
Completed
Not Applicable
Diagnostic accuracy of minimally-invasive biomarkers for sputum eosinophilia in adult-onset asthma patients.
Academic Medical Center, Amsterdam0 sites336 target enrollmentTBD
Conditionsadult-onset asthmasputum eosinophilia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- adult-onset asthmasputum eosinophilia
- Sponsor
- Academic Medical Center, Amsterdam
- Enrollment
- 336
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age: 18\-75 years
- •Physician’s diagnosis of asthma, combined with documented reversibility in FEV1 of \> 12% of predicted value or a positive inhaled methacholine provocation test (PC20 \< 8mg/ml) or diurnal variation in PEF of \>20% (with twice daily reading \>10%)
Exclusion Criteria
- •Smoking history of \>10 pack years combined with fixed airflow obstruction (FEV1 \<80% of predicted and FEV1/FVC \<0\.70\) without reversibility in FEV1 \<12% or with a diffusion capacity \<80% (TLCO/VA).
- •Other pulmonary diseases.
Outcomes
Primary Outcomes
Not specified
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