IRCT20200304046698N2招募中3 期
Evaluation of the effectiveness of metformin prophylaxis in preventing risperidone-induced hyperprolactinemia in children and adolescents
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 10 years 至 18 years（—）
- 性别
- All
入选标准
- •Patient and parent consent to participate in the study
- •Age 10 to 18 years
- •Psychiatric necessity for taking risperidone
- •Normal prolactin at the beginning of the study
排除标准
- •Allergy to risperidone or metformin
- •Need to change risperidone or add a second drug due to lack of control of psychiatric symptoms
- •Intolerable or severe side effects with risperidone and metformin
- •Occurrence of short-term physical symptoms of hyperprolactinemia
- •Previous or current history of neurological disease (current seizure disorders, history of head trauma, migraine)
- •Previous or current history of systemic disease (blood, endocrine, liver, thyroid, kidney, metabolic disease)
- •Smoking and any type of drug
- •Taking medication that interacts with metformin
- •Positive pregnancy test in teenage girls
- •Taking any type of drug affecting the plasma level of prolactin (including other antipsychotics, antidepressants, and stimulants)
研究者
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