MedPath

Multicenter, open-label extension study to investigate the long-term safety and efficacy of IgPro20 in maintenance treatment of chronic inflammatory demyelinating polyneuropathy (CIDP) in subjects completing study IgPro20_3003.

Phase 3
Completed
Conditions
peripheral nerve damage
polyneuropathy
10021460
10012303
Registration Number
NL-OMON44389
Lead Sponsor
CSL Behring GmbH
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
3
Inclusion Criteria

1. Written informed consent for study IgPro20_3004 before any study-specific procedures are performed.
2. Subject has completed the pivotal study IgPro20_3003 (SC Week 25), or was successfully rescued from a CIDP relapse during the SC Treatment Period of study IgPro20_3003.

Exclusion Criteria

1. Subject is unable to directly transition from the pivotal study IgPro20_3003, ie, the subject is unable to have the baseline visit conducted at the same time as the completion visit for the pivotal study IgPro20_3003.
2. New medical condition and/or social behavior (ie, alcohol, drug, or medication abuse) during participation in pivotal study IgPro20_3003 that in the judgment of the investigator could increase risk to the subject, interfere with the evaluation of IMP, and/or conduct of the study. See Section 6.7 (Contraindications and Precautions for Further Dosing).
3. Pregnant or intention to become pregnant during the course of the study.
4. Female subjects of childbearing potential either not using, or not willing to continue to use, a medically reliable method of contraception for the entire duration of the study, or not sexually abstinent for the entire duration of the study, or not surgically sterile.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Primary endpoint:<br /><br>* Overall rate of AEs per infusion.</p><br>
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath