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Clinical Trials/NCT05149950
NCT05149950
Active, not recruiting
Not Applicable

Internet Treatment for Patients With Obesity - a Randomized Study

Region Örebro County1 site in 1 country100 target enrollmentJanuary 3, 2022
ConditionsObesity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity
Sponsor
Region Örebro County
Enrollment
100
Locations
1
Primary Endpoint
Obesity-specific quality of life
Status
Active, not recruiting
Last Updated
7 months ago

Overview

Brief Summary

There is a strong link between obesity and reduced quality of life as well as serious sequelae of diseases. Step by step is a treatment model that has been developed at the Obesity Unit, Orebro County Region and includes six group meetings over 6-8 months. The aim is to increase patients' knowledge about the disease obesity, to provide support for lifestyle changes and weight control, and to reduce stigma-related psychosocial disorders. A 1-year pilot study aimed at evaluating the Internet-based Step by Step treatment has recently been completed. Results after 6 months of treatment show that the participants who completed the treatment were mainly satisfied with the program and the content. However, the dropouts from the treatment were more than expected.

Detailed Description

Based on the experience from the pilot study, a new randomized study is planned with the aim of evaluating a revised treatment program. People 25-69 years with a BMI 30-44.9 kg / m2, or with a BMI 28-29.9 kg / m2 and co-occurrence of hypertension, prediabetes, type 2 diabetes, coronary heart disease, hyperlipidemia, hepatic steatosis, sleep apnea or polycystic ovary syndrome can be included. The intervention group receives increased therapist support with physical or digital meetings before and during the treatment as well as individualized feedback from the therapist. Feedback takes place after 6, 12 and 18 weeks. The other group, the control group, implements the program without meetings with the therapist and receives general feedback during the treatment. The purpose is to evaluate whether increased therapist contact compared to less therapist contact leads to improved weight reduction, quality of life, eating habits and increases physical activity at follow-up after 12 months

Registry
clinicaltrials.gov
Start Date
January 3, 2022
End Date
November 30, 2025
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Region Örebro County
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • BMI 30-44.9 kg / m2
  • BMI 28-29.9 kg / m2 and hypertension
  • BMI 28-29.9 kg / m2 and prediabetes
  • BMI 28-29.9 kg / m2 and type 2 diabetes
  • BMI 28-29.9 kg / m2 and coronary heart disease
  • BMI 28-29.9 kg / m2 and hyperlipidemia
  • BMI 28-29.9 kg / m2 and hepatic steatosis
  • BMI 28-29.9 kg / m2 and sleep apnea
  • BMI 28-29.9 kg / m2 and polycystic ovary syndrome

Exclusion Criteria

  • Severe mental illness
  • Ongoing or suspected eating disorder
  • Pregnancy
  • Breastfeeding
  • Cancer in active treatment
  • Use of drugs for weight loss
  • Weight loss treatment during the past 6 months
  • Active abuse of alcohol or drugs
  • Not being able to express themselves in Swedish in speech and writing
  • If the study supervisor deems that participation in the study is inappropriate for another reason.

Outcomes

Primary Outcomes

Obesity-specific quality of life

Time Frame: 12 months

Avoidant social behavior due to obesity-related psychosocial disorders which is measured with the Obesity-related Problems scale "(OP)". The OP scale is validated to measure obesity-specific quality of life. OP measures the negative effects of obesity on psychosocial functioning and is useful for evaluating the effects of obesity interventions on quality of life. Scores range from 0 to 100, and higher scores indicate dysfunction.

Secondary Outcomes

  • Proportion of participants with ≥ 5% weight reduction(6 and 12 months)
  • Dietary habits(6 and 12 months)
  • Weight reduction as a percentage of body weight before treatment(6 and 12 months)
  • General health-related quality of life(6 and 12 months)
  • Physical activity(6 and 12 months)
  • Eating behavior(6 and 12 months)
  • Obesity-specific quality of life: psychosocial distress(6 and 12 months)
  • Physical activity measured with an accelerometer(During 7 days before treatment and at 6 and 12 months)
  • Sleep quality(6 and 12 months)
  • Completion of the treatment program(6 and 12 months)
  • The participants' experiences and experiences of the treatment(Every three weeks up to 24 weeks)

Study Sites (1)

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