Ingestion of probiotics (a Lactobacillus rhamnosus formula) as complementary therapy in the treatment of patients with plaque psoriasis (an inflammatory disease of the skin)

Not Applicable

• Conditions: Psoriasis; C17.800

• Registration Number: RBR-8js7t83
• Lead Sponsor: Enrico Stefano Suriano

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2022-03-20
• Study Start: 2022-08-02
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Being over 18 years old; having plaque psoriasis.

Exclusion Criteria

Being pregnant; having other skin diseases, neoplasms or systemic inflammatory diseases (such as Crohn’s disease, inflammatory bowel disease, vasculitis and sarcoidosis).

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in mean PASI (Psoriasis Area of Severity Index). In the beginning of the study, we expected to find a difference of 30% between groups after 6 months of administration of probiotics. After the study was completed, the observed difference was of 20% (reduction of mean PASI of 3.06 in the experimental group and of 2.46 in the control group, with p=0.62).