IRCT2013041613027N1已完成未知
The Comparative study about effect of Donepezil with and without Memantine on recovery of cognitive, linguistic dysfunctions and disability rating in traumatic brain injury patients during the subacute phase
Research adjutancy ,Guilan university of medical sciences0 个研究点目标入组 162 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 162
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 60 years（—）
- 性别
- All
入选标准
- •aphasia patients having post-traumatic cognitive deficit; moderate & severe traumatic brain injury according to GCS at first 24 h; age range between 18-60 years; GOS score 4 & 5; at least 4 years formal education; maximum of aphasia quotient 75 based on P.AD; moderate and severe cognitive deficit(MMSE score<17); post onset discharge time 2-4 weeks(sub-acute phase).
- •Exclusion criteria: history of neurological disease including CVA, brain tumor, epilepsy, seizure, Parkinson and dementia...; previous brain trauma; history of psychiatric disorder and using of antipsychotic & antidepressant drugs; history of drug abuse and pre-existing verbal and cognitive deficit; exist of deafness and blindness; appearance of drug's side effects; exist of renal disease, heart disease, hypertension and unwillingness for continue of the study.
排除标准
- 未提供
研究者
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