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Clinical Trials/NCT02576223
NCT02576223
Completed
Not Applicable

Suprascapular Nerve Block as Postoperative Analgesia After Artroscopic Shoulder Surgery - a Randomized, Blinded, Placebo Controlled Study

Kai Henrik Wiborg Lange2 sites in 1 country40 target enrollmentOctober 2015

Overview

Phase
Not Applicable
Intervention
Ropivacaine hydrochloride
Conditions
Pain
Sponsor
Kai Henrik Wiborg Lange
Enrollment
40
Locations
2
Primary Endpoint
Visual analogue scale (VAS) score at rest at T½
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this randomized study is to examine the effect of a selective suprascapular nerve block on post operative pain after arthroscopic shoulder surgery. Half of the subjects will receive a active nerve block with Ropivacain. Half of the subjects will receive a placebo nerve block with saline.

Detailed Description

Postoperative pain management after arthroscopic shoulder surgery traditionally includes opioids and/or an interscalene brachial plexus block(IBPB). Opioid consumption often leads to unpleasant side effects including nausea, vomitting and sedation. IBPB offers very efficient pain relief but includes the discomfort of a paralyzed arm. Furthermore this approach often also leads to unilateral paresis of the phrenic nerve causing reduced respiratory capacity. The latter offering discomfort and a potential risk in patients with lung diseases or heavy overweight. The suprascapular nerve is the most important nerve to the shoulder and a selective block of this nerve could offer a good pain relief without the mentioned side effects. In this randomized study the investigators wish to examine the pain relieving effect of a selective block of the suprascapular nerve after arthroscopic shoulder surgery. 40 patients are randomized to a block of this nerve with either active drug (Ropivacaine) or placebo (Saline). All patients will get a PCA (Patient Controlled Analgesia) pump for administration of i.v. morphine in doses based on age and weight. Patient are being monitored for 6 hours. The primary outcome is reduction in VAS at rest from baseline to 30 minutes after nerve block.

Registry
clinicaltrials.gov
Start Date
October 2015
End Date
August 27, 2018
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Kai Henrik Wiborg Lange
Responsible Party
Sponsor Investigator
Principal Investigator

Kai Henrik Wiborg Lange

Head of Research

Hillerod Hospital, Denmark

Eligibility Criteria

Inclusion Criteria

  • Patients planned for arthroscopic shoulder surgery.
  • ASA class ≤ 3.

Exclusion Criteria

  • Patients with VAS never ≥5 mm during the first hour after arrivel to the post anesthesia care unit.
  • Patients unable to cooperate.
  • Patients unable to understand or speak danish.
  • Allergy towards the used drugs.
  • Abuse of alcohol- and/or medicine - investigators assessment.
  • Usage of opioids on a daily basis (not including Tramadole).
  • Pregnancy (It is obligatory for all fertile women in the study to take a hcg urine test).
  • Operations involving the clavicle.
  • Operations converted to open surgery.

Arms & Interventions

Ropivacaine hydrochloride

Ropivacain 7.5mg/ml, 5 ml injected perineural at the suprascapular nerve.

Intervention: Ropivacaine hydrochloride

Ropivacaine hydrochloride

Ropivacain 7.5mg/ml, 5 ml injected perineural at the suprascapular nerve.

Intervention: PCA-pump

Isotonic Saline

0.9% Saline solution, 5 ml injected perineural at the suprascapular nerve.

Intervention: Isotonic Saline

Isotonic Saline

0.9% Saline solution, 5 ml injected perineural at the suprascapular nerve.

Intervention: PCA-pump

Outcomes

Primary Outcomes

Visual analogue scale (VAS) score at rest at T½

Time Frame: Baseline to 30 minutes

Change in VAS score at rest from baseline to 30 minutes after nerve block (T½).

Secondary Outcomes

  • VAS score during maximum active shoulder abduction from T½ to T6(½, 1, 2, 3, 4, 5, 6 hours)
  • Morphine consumption.(6 hours)
  • VAS score at rest from T½ to T6(½, 1, 2, 3, 4, 5, 6 hours)
  • Muscle strength at T½(Baseline to 30 minutes)
  • Electromyography at T½(Baseline to 30 minutes)

Study Sites (2)

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