The hemodynamic effect of the passive leg raising maneuver on propofol-induced hypotension during induction of general anesthesia - a randomized clinical trial

Not Applicable

Conditions: I95.2
Hypotension due to drugs

Registration Number: DRKS00032275

Lead Sponsor: Klinik für Anästhesiologie und Operative Intensivmedizin, UNIVERSITÄTSKLINIKUM Schleswig-Holstein, Campus Kiel

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 150

Inclusion Criteria

elective surgery under general anesthesia (total intravenous or balanced general anesthesia) with the induction drugs sufentanil, propofol and rocuronium
- ASA status I, II or III
- Patient consent

Exclusion Criteria

- Marked edema or skin defects on the patient's fingers or hand
- Heart failure (New York Heart Association (NYHA) stage II or greater)
- Atrial fibrillation or other higher-grade cardiac arrhythmia
- peripheral arterial disease (Fontaine stage > 2)
- central regional anesthesiology procedures
- suspected or documented difficult airway
- induction of anesthesia as rapid sequence induction

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recording of differences in mean arterial blood pressure (MAP) readings in the control and intervention groups during the study period

Secondary Outcome Measures

Name	Time	Method
1. Capture of the incidence of cumulative time (= minutes of severe hypotension (MAP < 65 mmHg)) within the study period in the control and intervention groups.<br>2. Determination of the time-weighted mean value of MAP below threshold (< 65 mmHg) within the study period in the control and intervention groups. <br>3. Pointing out the difference in the absolute dose of vasopressors administered in the control and intervention groups within the study period.