Interest of Hypnosis Before the Induction of Anesthesia. Study in Women Submitted to One Day Gynecological Surgical Procedures
Overview
- Phase
- Not Applicable
- Intervention
- Control
- Conditions
- Anesthesia
- Sponsor
- Hopital Foch
- Enrollment
- 80
- Locations
- 1
- Primary Endpoint
- Administered dose of propofol
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Hypnosis may reduce patient anxiety. The main goal of this study is to determine in what extent, hypnosis decreases propofol requirement to induce induction of general anesthesia.
Two particular aspects of this study are
- the inclusion of women undergoing one day gynecological surgical procedures
- the use of a closed-loop system which delivers propofol according to bispectral index to provide induction of anesthesia.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adult female patients scheduled for a one day gynecological surgical procedures under general anesthesia
Exclusion Criteria
- •pregnancy, breast feeding woman
- •allergy to propofol, soy or peanuts
- •history of central nervous system disease
- •psychiatric affection
- •hypovolemia, high cardiovascular risk
- •patients with a pace-maker
Arms & Interventions
Control
Standard care without hypnosis session followed by closed-loop administration of propofol for anesthesia induction
Intervention: Control
Control
Standard care without hypnosis session followed by closed-loop administration of propofol for anesthesia induction
Intervention: propofol
Hypnosis
Hypnosis session followed by closed-loop administration of propofol for anesthesia induction
Intervention: Hypnosis
Hypnosis
Hypnosis session followed by closed-loop administration of propofol for anesthesia induction
Intervention: propofol
Outcomes
Primary Outcomes
Administered dose of propofol
Time Frame: one hour
Administered dose of propofol required to obtain the induction of anesthesia (bispectral index \<60 for at least 30 seconds)
Secondary Outcomes
- Pain due to injection of propofol(one hour)
- Pain of insertion of peripheral vein catheter(one hour)
- Effect of hypnosis on bispectral index(one hour)
- Time to loss of consciousness(one hour)
- Hemodynamic consequences of induction of anesthesia(one hour)
- Administration of a cardio-vascular agent(one hour)
- Manipulation of the airway(one hour)
- Characteristics of the hypnotic procedure evaluated by the clinician in the group "hypnosis"(one hour)
- Characteristics of the hypnotic procedure evaluated by the patient in the group "hypnosis"(six hours)
- Characteristics of the preanesthetic management evaluated by the patient (all the patients)(Six hours)
- Target plasma concentration of propofol(one hour)