To relieve post operative sore throat and cough after general anesthesia procedure

Phase 4

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2022/06/043373
• Lead Sponsor: MADHURI G

Brief Summary

Postoperative sore throat (POST) is one of the most common, undesirable and neglected complaint in patients following endotracheal intubation during general anaesthesia. We hypothesize that dextromethorphan in routine anti-tussive doses, would be effective to prevent POST thus improving patient recovery and satisfaction scores.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-06-17
• Study Start: 2022-06-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• 1.Adult patients between 18-60 yr of age of either sex.
• 2.ASA status I, II ,III Undergoing elective surgeries under general anesthesia with ETT tube in prone and supine position.
• 3.Patients posted for surgeries more than 1hr and lasting upto 6hrs.

Exclusion Criteria

• 1.Patients refusing to participate in the study 2.Patient posted for surgeries lasting more than 6hrs 3.Surgery involving the oral cavity, nasopharynx, larynx and neck regions.
• 4.History of preoperative sore throat, common cold, anticipated difficult airway.
• 5.Pregnant or lactating mothers.
• 6.Recent use of anti-inflammatory drugs 7.Allergic to study drug 8.On other centrally acting medications 9.Immune deficiencies 10.History of difficult intubation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•Assess the severity of post-operative sore throat in the study group	To assess severity at 1 , 6 and 24hours

Secondary Outcome Measures

Name	Time	Method
•To assess the degree of post-operative hoarseness of voice and cough	To assess severity at 1 , 6 and 24 hours

Trial Locations

Locations (1)

Rajarajeshwari medical College and hospital; 🇮🇳 Bangalore, KARNATAKA, India

Rajarajeshwari medical College and hospital

🇮🇳Bangalore, KARNATAKA, India

Dr MADHURI

Principal investigator

8861840505

gmadhuri7914@gmail.com