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Labor and Delivery Implant Insertion: A Randomized Controlled Trial

Phase 3
Completed
Conditions
Family Planning
Postpartum Contraception
Interventions
Drug: Etonogestrel-Immediate
Drug: Etonogestrel-Delayed
Registration Number
NCT02866643
Lead Sponsor
Stanford University
Brief Summary

A barrier to initiating progestin contraceptives in the early postpartum period is the concern of interference with breastfeeding, specifically lactogenesis. In this trial, the investigators aim to describe the effects of immediate insertion of the contraceptive implant on breastfeeding. The investigators seek to examine the time to lactogenesis with immediate post-delivery insertion in delivery room versus insertion of a contraceptive implant in the postpartum ward prior to medical discharge. For this study, 82 consenting women will be randomized to immediate implant insertion (0-2 hours following delivery) in the delivery room or insertion of the implant following delivery in postpartum room and prior to medical discharge (24-48 hours following delivery).

Participants complete a questionnaire that asks questions about breastfeeding continuation, supplementation, duration, and exclusivity. This questionnaire also includes questions about contraceptive continuation, patient satisfaction with implant, pregnancy, and postpartum care visits.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
95
Inclusion Criteria
  • Pregnant women who are patients of the Stanford University Obstetrics service
  • Pregnant women who delivery a healthy infant, regardless of gestational age.
  • Intend to breastfeed
  • Desire the contraceptive implant as their method of contraception
  • Agree to be randomized to delivery room vs. postpartum ward insertion
Exclusion Criteria
  • Not English or Spanish speaking
  • Allergy or Contraindication to contraceptive implant.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Delivery Room InsertionEtonogestrel-ImmediateParticipants who randomize to this arm will receive the contraceptive implant in the Labor and Delivery room (0-2 hours following delivery).
Postpartum InsertionEtonogestrel-DelayedParticipants who randomize to this arm will receive the contraceptive implant in the postpartum ward room before discharge (24-48 hours following delivery).
Primary Outcome Measures
NameTimeMethod
Time to Lactogenesis Stage II [Questionnaire]Participants will be monitored daily by the research staff, in the first seven days postpartum, or until lactogenesis reported, beginning at 24-hours following delivery, to determine time to lactogenesis stage II.

Lactogenesis Stage II: The initiation of copious milk secretion as documented by maternal perception.

To obtain measurement of time to lactogenesis, we will document time at which participants perceive initiation of copious milk secretion using a set of specific validated questions and subtract this by the documented time of delivery.

Secondary Outcome Measures
NameTimeMethod
Number of Participants Still With the Contraceptive Implant at Month 12.month 12
Number of of Participants Actively Breastfeeding2 weeks, 4 weeks, 3 months, 6 months, and 12 months after delivery

Exclusive breastfeeding means feedling with breast milk only. Any breast feeding means feeding with breast milk, with water and/or formula.

Number of Participants Reporting a Pregnancy Within 12 Months12 months
Number of Participants Attending a Postpartum Care Visit by Month 3month 3
Number of Participants Satisfied or Very Satisfied With Implant Contraceptivemonth 12

Participant-rated as very satisfied, satisfied, neither satisfied or dissatisfied, dissatisfied, or very dissatisfied.

Trial Locations

Locations (1)

Obstetrics--Lucile Packard Children's Hospital

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Stanford, California, United States

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