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Clinical Trials/NCT02866643
NCT02866643
Completed
Phase 3

Labor and Delivery Implant Insertion: A Randomized Controlled Trial

Stanford University1 site in 1 country95 target enrollmentOctober 28, 2016

Overview

Phase
Phase 3
Intervention
Etonogestrel-Immediate
Conditions
Postpartum Contraception
Sponsor
Stanford University
Enrollment
95
Locations
1
Primary Endpoint
Time to Lactogenesis Stage II [Questionnaire]
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

A barrier to initiating progestin contraceptives in the early postpartum period is the concern of interference with breastfeeding, specifically lactogenesis. In this trial, the investigators aim to describe the effects of immediate insertion of the contraceptive implant on breastfeeding. The investigators seek to examine the time to lactogenesis with immediate post-delivery insertion in delivery room versus insertion of a contraceptive implant in the postpartum ward prior to medical discharge. For this study, 82 consenting women will be randomized to immediate implant insertion (0-2 hours following delivery) in the delivery room or insertion of the implant following delivery in postpartum room and prior to medical discharge (24-48 hours following delivery).

Participants complete a questionnaire that asks questions about breastfeeding continuation, supplementation, duration, and exclusivity. This questionnaire also includes questions about contraceptive continuation, patient satisfaction with implant, pregnancy, and postpartum care visits.

Registry
clinicaltrials.gov
Start Date
October 28, 2016
End Date
July 31, 2021
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Kate Ayers Shaw

Clinical Associate Professor

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Pregnant women who are patients of the Stanford University Obstetrics service
  • Pregnant women who delivery a healthy infant, regardless of gestational age.
  • Intend to breastfeed
  • Desire the contraceptive implant as their method of contraception
  • Agree to be randomized to delivery room vs. postpartum ward insertion

Exclusion Criteria

  • Not English or Spanish speaking
  • Allergy or Contraindication to contraceptive implant.

Arms & Interventions

Delivery Room Insertion

Participants who randomize to this arm will receive the contraceptive implant in the Labor and Delivery room (0-2 hours following delivery).

Intervention: Etonogestrel-Immediate

Postpartum Insertion

Participants who randomize to this arm will receive the contraceptive implant in the postpartum ward room before discharge (24-48 hours following delivery).

Intervention: Etonogestrel-Delayed

Outcomes

Primary Outcomes

Time to Lactogenesis Stage II [Questionnaire]

Time Frame: Participants will be monitored daily by the research staff, in the first seven days postpartum, or until lactogenesis reported, beginning at 24-hours following delivery, to determine time to lactogenesis stage II.

Lactogenesis Stage II: The initiation of copious milk secretion as documented by maternal perception. To obtain measurement of time to lactogenesis, we will document time at which participants perceive initiation of copious milk secretion using a set of specific validated questions and subtract this by the documented time of delivery.

Secondary Outcomes

  • Number of of Participants Actively Breastfeeding(2 weeks, 4 weeks, 3 months, 6 months, and 12 months after delivery)
  • Number of Participants Reporting a Pregnancy Within 12 Months(12 months)
  • Number of Participants Attending a Postpartum Care Visit by Month 3(month 3)
  • Number of Participants Still With the Contraceptive Implant at Month 12.(month 12)
  • Number of Participants Satisfied or Very Satisfied With Implant Contraceptive(month 12)

Study Sites (1)

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