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Effect of Mexiletine on depth of anesthesia

Not Applicable
Conditions
B.I.Sindex,B.P,H.R.
Injuries to upper extrimity
S40-S41_S4
Registration Number
IRCT201109067488N1
Lead Sponsor
Kerman University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
50
Inclusion Criteria

Inclusion Criteria:Patients scheduled for upper limb orthopedic surgery under G.A with A.S.A 1,2,aged 20-60 yrs.

Exclusion Criteria

Liver disorders,positive history of sensitivity to local anesthetic drugs,bradycardia ,pregnant and neursing women, seizure disorders,C.N.S problems and heart blocks . patients in whom more than 15 sec were required for tracheal intubation were excluded from the study

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
B.I.S index. Timepoint: Before and 3 minutes after induction of anesthesia and 1,3.10minutes after intubation ,incision of surgery and every 15 minutes till the end of operation. Method of measurement: monitoring of depth of anesthesia.;Systolic Blood pressur. Timepoint: Before and 3 minutes after induction of anesthesia and 1,3.10minutes after intubation ,incision of surgery and every 15 minutes till the end of operation. Method of measurement: mmhg by NIBP Monitoring.;Diastolic Blood pressur. Timepoint: Before and 3 minutes after induction of anesthesia and 1,3.10minutes after intubation ,incision of surgery and every 15 minutes till the end of operation. Method of measurement: mmgh by NIBP manitoring.;Heart Rate. Timepoint: Before and 3 minutes after induction of anesthesia and 1,3.10minutes after intubation ,incision of surgery and every 15 minutes till the end of operation. Method of measurement: Heart Rate by electronic monitoring.
Secondary Outcome Measures
NameTimeMethod
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