跳至主要内容
临床试验/NCT00604916
NCT00604916已完成1 期

The Effectiveness of an Oral Care Protocol in Preventing Ventilator- Associated Pneumonia for Intensive Care Unit Patient

Mackay Memorial Hospital0 个研究点目标入组 53 人开始时间: 2007年3月1日最近更新:
适应症
干预措施

试验速览

阶段
1 期
状态
已完成
入组人数
53
主要终点
the oral hygiene status measured by the oral assessment guide and plague index

研究概览

简要总结

The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms. Research indicates that the Gram-Negative Bacteria grows in upper air way and trachea rapidly during the initial 2-4 hospital days and the dental plague also increased dramatically at the first 5 days. About 50% cases with prolonged intubation experienced temporal swallowing disorders and majority of them recovered 7 days post weaning. Some evidence exist suggesting that oral care could reduce bacterial flora, prevent aspiration, and subsequently decrease the incidence of ventilation-associated pneumonia for this group of high risk patients.

This study aims to evaluate the effectiveness of a standardized oral care protocol in improving oral hygiene and reducing the incidence of pneumonia on a sample of surgical patients at intensive care unit.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Prevention
盲法
Single (Investigator)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients newly admitted to SICU who were under ventilator support for 48~72 hours

排除标准

  • •With pneumonia present

研究组 & 干预措施

E

Experimental

received a 7 day standardized oral care protocol

干预措施: standardized oral care protocol - electronic toothbrush (Other)

C

Placebo Comparator

received a 7 day mimic protocol

干预措施: mimic protocol (Other)

结局指标

主要结局

the oral hygiene status measured by the oral assessment guide and plague index

时间窗: every 3~4days

次要结局

  • The incidence of VAP defined by the Clinical Pulmonary Infection Score(a 7 day oral care protocol duration)

研究者

申办方类型
Other

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