The Effectiveness of an Oral Care Protocol in Preventing Ventilator- Associated Pneumonia for Intensive Care Unit Patient
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 53
- 主要终点
- the oral hygiene status measured by the oral assessment guide and plague index
研究概览
简要总结
The Nosocomial Pneumonia remains to be a major complication for patients who were incubated with ventilation. Most cases are attributed to increased bacteria flora in oropharyngeal secretion and aspiration of those organisms. Research indicates that the Gram-Negative Bacteria grows in upper air way and trachea rapidly during the initial 2-4 hospital days and the dental plague also increased dramatically at the first 5 days. About 50% cases with prolonged intubation experienced temporal swallowing disorders and majority of them recovered 7 days post weaning. Some evidence exist suggesting that oral care could reduce bacterial flora, prevent aspiration, and subsequently decrease the incidence of ventilation-associated pneumonia for this group of high risk patients.
This study aims to evaluate the effectiveness of a standardized oral care protocol in improving oral hygiene and reducing the incidence of pneumonia on a sample of surgical patients at intensive care unit.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients newly admitted to SICU who were under ventilator support for 48~72 hours
排除标准
- •With pneumonia present
研究组 & 干预措施
E
received a 7 day standardized oral care protocol
干预措施: standardized oral care protocol - electronic toothbrush (Other)
C
received a 7 day mimic protocol
干预措施: mimic protocol (Other)
结局指标
主要结局
the oral hygiene status measured by the oral assessment guide and plague index
时间窗: every 3~4days
次要结局
- The incidence of VAP defined by the Clinical Pulmonary Infection Score(a 7 day oral care protocol duration)
