The effect of tDCS on elderly with depression and cognitive impairment

Yonsei University Health System, Severance Hospital0 个研究点目标入组 50 人开始时间: 待定最近更新: 2023年2月8日

试验速览

暂无简介。

•1) Adults aged 60 years or older to under 90 years of age who visited a dementia safety center or hospital
•2) A person who subjectively complains of memory impairment or meets the criteria for diagnosis of mild cognitive impairment;
•- Subjective Memory Complaints Questionnaire (SMCQ) answered yes to one or more items, but other objective cognitive tests (SNSB or CERAD) fall into the normal category)
•- Mild cognitive impairment is defined as the fraction in which daily life is maintained in society and home, although neuropsychological tests such as CERAD or SNSB show a 1.5 standard deviation from the average value of normal controls considering age and education.
•3) A person who is diagnosed as suitable for elderly depression through a clinical interview with a psychiatrist (S-GDS = 5 points or higher)
•- One or more major symptoms of depression (diagnosis of mental illness, thoughts of repeated death, or suicide) such as decreased mood, decreased interest or pleasure in daily activities, altered weight or appetite, insomnia or excessive sleep, fatigue or loss of vitality, loss of thought or focus, or suicide.
•4) A person who is able to read and understand the subject's explanatory statement and consent, and speaks Korean;
•5) Right-handed
•6) A person who voluntarily decides to participate in this clinical trial and agrees in writing to the automatic examination will and is permitted to participate in the pre-clinical trial period;

•1) A person who has been found to have other neurological abnormalities that may cause memory impairment in medical examinations;
•2) A person who has a history of one-axis psychiatric disorders including intellectual disability, schizophrenia, alcoholism, and bipolar disorder in the past
•3) A person who reports continuous suicide incidents
•4) Where it is deemed that there is a problem in attaching electroencephalons and direct current stimulation electrodes due to abnormalities, inflammatory reactions, or other dermatological problems of the scalp;
•5) A person who has been treated with medical diagnosis that may interfere with participation in this experiment, such as stroke, convulsive disease, Parkinson's disease, multiple sclerosis, cerebral palsy, huntington's disease, encephalitis, meningitis, liver disease beyond cirrhosis, and kidney disease requiring dialysis;
•6) A person who has undergone surgery on cerebral blood vessels, such as brain surgery or carotid artery surgery;
•7) A person who is unable to understand a conversation due to hearing impairment even with hearing aids on;
•8) A person who is unable to read letters even with glasses on due to a loss of vision;
•9) In addition to the above, a person who has clinical significance that the person in charge or the person in charge of the examination thinks is inappropriate for this examination 1) A person who has found other neurological abnormalities that may cause memory impairment.

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