Longitudinal and Biological Study of Childhood Disintegrative Disorder
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 220
- 试验地点
- 2
研究概览
简要总结
OBJECTIVES:
I. Compare the developmental course (language acquisition, diagnostic stability, predictors of outcome, and restricted interests and behaviors) of childhood disintegrative disorder versus autism and non-autistic developmental delays.
II. Collect data on molecular genetics of proband and family members.
详细描述
PROTOCOL OUTLINE:
Patients are evaluated with the following questionnaires at ages 2-3 years and again at ages 5-9: The Autism Diagnostic Interview (ADI); The Autism Diagnostic Observation Schedule (ADOS); Assessment of cognitive functioning; Expressive and receptive language; Adaptive functioning; Measures of burden and functional assessment; The Aberrant Behavior Checklist; The Connors Rating Scale - Parent and Teacher version; and Autism Behavior Checklist
An MRI and EEG are performed, and blood samples are collected from patients and family members for molecular genetic studies.
研究设计
- 研究类型
- Observational
- 时间视角
- Other
入排标准
- 年龄范围
- 2 Years 至 9 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供