Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.
Not Applicable
Completed
- Conditions
- High Myopia
- Interventions
- Device: MPS II
- Registration Number
- NCT02205632
- Lead Sponsor
- Poitiers University Hospital
- Brief Summary
Lutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area.
Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density.
Reduced macular pigment level is a significant risk factor for age-macular degeneration. The nutritional intake can minimise the risk of age-macular degeneration.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 39
Inclusion Criteria
- Age >18 years-old
- High axial myopia < -6 dioptries
- Presence or not of lacquer cracks in Bruch's membrane in one or both eyes
- Patients with social security coverage
Exclusion Criteria
- Age <18 years-old
- Amblyopia in the studied eye
- Prior ocular surgery
- Corneal disease or severe dry eye syndrome
- Other retinal disease: diabetic retinopathy, age-related macular degeneration, macular hole, epiretinal membrane central
- Extensive chorioretinal atrophy
- Allergy to tropicamide
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description High myopic patients with lacker craks MPS II - High myopic patients without lacker cracks MPS II -
- Primary Outcome Measures
Name Time Method Association between lacquer cracks related to high myopia and the macular pigment optical density 1 day
- Secondary Outcome Measures
Name Time Method The macular pigment optical density among high myopic patients 1 day
Trial Locations
- Locations (1)
ophthalmology department, Poitiers University Hospital
🇫🇷Poitiers, Vienne, France