NCT02205632已完成不适用
Relationships Between Macular Pigment Optical Density and Lacquer Cracks in High Myopic Patients.
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 试验地点
- 2
- 主要终点
- Association between lacquer cracks related to high myopia and the macular pigment optical density
研究概览
简要总结
Lutein ans zeaxanthin, carotenoids provided by dietary intake are mainly located in the macular area.
Its absorption peak at 460 nm may reduce photic damages. The macular pigment density can be evaluated by its optical density.
Reduced macular pigment level is a significant risk factor for age-macular degeneration. The nutritional intake can minimise the risk of age-macular degeneration.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age >18 years-old
- •High axial myopia < -6 dioptries
- •Presence or not of lacquer cracks in Bruch's membrane in one or both eyes
- •Patients with social security coverage
排除标准
- •Age <18 years-old
- •Amblyopia in the studied eye
- •Prior ocular surgery
- •Corneal disease or severe dry eye syndrome
- •Other retinal disease: diabetic retinopathy, age-related macular degeneration, macular hole, epiretinal membrane central
- •Extensive chorioretinal atrophy
- •Allergy to tropicamide
- •Pregnancy
研究组 & 干预措施
High myopic patients with lacker craks
Other
干预措施: MPS II (Device)
High myopic patients without lacker cracks
Other
干预措施: MPS II (Device)
结局指标
主要结局
Association between lacquer cracks related to high myopia and the macular pigment optical density
时间窗: 1 day
次要结局
- The macular pigment optical density among high myopic patients(1 day)
研究者
研究点 (2)
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