The effect of chemotherapy-induced QT prolongation on all-cause mortality in cancer patients-a retrospective observational cohort study
Not Applicable
- Conditions
- Diseases of the circulatory system
- Registration Number
- KCT0006836
- Lead Sponsor
- ational Cancer Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 13032
Inclusion Criteria
Over 19 years old.
Patients treated with anticancer drugs(39 types) that can extend the QT interval at the National Cancer Center
Patients who underwent an electrocardiogram
Exclusion Criteria
Under 18 years of age
It's hard to evaluate QT due to electrocardiogram
QRS duration>120ms
complete left or right bundle branch blocks, intraventricular conduction delays
ventricular pacing
atrial fibrillation/flutter
second-degree and complete artial-ventricular blocks
severely sinus, atrial and ventricular tachyarrhythmia
acute coronary sundrome with dynamic ST-T that interfered accurate QT assessment
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In cancer patients treated with QT-extended anticancer drugs, all cause deaths are confirmed within two years depending on the presence or absence of severe QT extension.
- Secondary Outcome Measures
Name Time Method The effect of extending QT by cancer type and anticancer drug on all causative deaths within 2 years