Resilience to Sleep Deprivation and Changes in Sleep Architecture in Shoonya Meditators
概览
- 阶段
- 不适用
- 干预措施
- Nap Practitioners
- 疾病 / 适应症
- Sleep
- 发起方
- Beth Israel Deaconess Medical Center
- 入组人数
- 75
- 试验地点
- 2
- 主要终点
- Error frequency Change: Go-No Go Task
- 状态
- 招募中
- 最后更新
- 10天前
概览
简要总结
This study aims to investigate the effect of a 15-minute meditation practice on sleep architecture and high-frequency Heart Rate Variability (HF-HRV), as well as cognitive performance after both a well-rested and sleep-deprived night.
详细描述
Sleep is physiologically important for memory consolidation, mood and hormonal regulation, and maintaining low levels of systemic inflammation. However, a substantial proportion of people are reported to regularly sleep less than the recommended 7-9 hours a night. Meditation may be a means to mitigate the negative effects of sleep deprivation, as many types of meditations are associated with increasing high-frequency heart rate variability (HF-HRV), which is an index of parasympathetic control of the heart. Greater parasympathetic drive may be associated with physiological buffering of the detrimental effects of sleep deprivation. The investigators want to conduct a prospective cohort study where subjects practice a 15-minute meditation (Shoonya meditation) or continue their usual routine. Subjects will be asked to complete some cognitive tests before and after a night of sleep and a night of sleep deprivation. During the night of sleep, participants will undergo polysomnography recording for sleep architecture and quality. The intervention group and the control group, which continues their usual routine, will only undergo one visit.
研究者
Balachundhar Subramaniam
Principal Investigator
Beth Israel Deaconess Medical Center
入排标准
入选标准
- •Shoonya meditation program participants/individuals eligible to participate who are healthy adults of age 18 or older, and reside in the United States. Participants must be able and willing to travel to Boston.
- •Nap Group: Healthy adults of age 18 or older that reside in the United States, nap regularly (at least 3 times a week), and do not meditate regularly.
排除标准
- •History of any neurological condition (i.e. Parkinson's disease, Alzheimer's disease, Huntington's disease, brain tumors, brain surgery, or multiple sclerosis)
- •History of any psychiatric disorder, within last 5 years (i.e. anxiety, psychosis, posttraumatic stress disorder, attention deficit hyperactive disorder)
- •Current use of cognition enhancing medications
- •Active history (within the last 5 years) of alcohol or drug abuse (\> 10 drinks per week)
- •History (within the last 5 years) of stroke/aneurysm
- •Recent history (\< 3 months) of seizures
- •60 years of age or older
- •History of Heart Attack and Ejection Fraction less than or equal to 30%
- •Non-English speaking
- •History/Diagnosis of any sleep disorder
研究组 & 干预措施
Nap Practitioners
This is an observational arm of regular nappers. Individuals that take naps at least two times a week will be invited to undergo all of the study procedures for one weekend of data collection.
干预措施: Nap Practitioners
Shoonya Meditators
This is intervention arm. Participants will learn and practice the fifteen minute shoonya meditation - described as a process of conscious non-doing- and shakti chalana kriya, which is a set of breathing exercises designed as a preparatory practice to shoonya meditation. Participants will practice shoonya meditation twice a day for two months. A weekend of data collection will happen at baseline and two months after they learn the practice.
干预措施: Shoonya Meditation
Control Meditators
Control subjects will be individuals that have learned the prerequisite meditation to Shoonya meditation. This meditation is called Shambhavi Mahamudra Kriya. Control subjects will not learn Shoonya meditation while they are participating in the study. One weekend of data collection will occur at baseline.
结局指标
主要结局
Error frequency Change: Go-No Go Task
时间窗: 2 months post learning meditation
The primary outcome is the difference in number of commission and omission errors on the Go-No Go task. The difference in scores pre- and post-sleep deprivation will be analyzed between the control and intervention group.
次要结局
- Reaction Time Change: Go-No Go(2 months post learning meditation)