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临床试验/NCT02919202
NCT02919202已完成不适用

A Randomised Controlled Trial Investigating a Comparison of Fluoride Varnish vs Self-Etching Dentine Bonding Agent in the Reduction of Cervical Dentine Sensitivity in Patients Attending a General Dental Practice in West Sussex, UK.

University of Kent2 个研究点 分布在 1 个国家目标入组 26 人开始时间: 2016年10月26日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
26
试验地点
2
主要终点
Visual Analogue Scale

研究概览

简要总结

This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex, UK. The participants will be split into 2 groups. One group will receive the intervention of topical fluoride varnish application while the other group will receive a topical application of self-etching dentine bonding agent.

详细描述

Topical Fluoride Varnish(TFV) and Self-Etching Dentine Bonding Agent (SEDBA) are both routinely used in dentistry in the management of cervical dentine sensitivity(CDS). Both interventions are topically applied and well tolerated by patients. The interventions differ in mechanism of action. TFV releases fluoride which is incorporated into the organic matrix of dentine making the dentine tubules less conductive. Dentinal tubules form the key conduit between stimulus and pain perception in the tooth. SEDBA differs in that it penetrates and occludes the tubules. It is light cured for an almost instant set time.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Exhibiting CDS elicited by the two test stimuli in relation at least one tooth.

排除标准

  • Patients who have undergone comprehensive periodontal treatment in the past 3 months.
  • Patients under the age of 18 or unable to provide valid consent.
  • Teeth that have visible fracture lines, caries, crowns or have been endodontically treated.
  • Patients taking analgesic medication for any systemic conditions.

结局指标

主要结局

Visual Analogue Scale

时间窗: 14 days

to measure pain/sensitivity perception

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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