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临床试验/ITMCTR2200005640
ITMCTR2200005640招募中1 期

To explore the mechanism of Yishen Tongluo formula affecting the apoptosis of varicocele vein endothelial cells in varicocele infertility patients based on PI3K/AKT/mTOR pathway

Henan Province Hospital of Traditional Chinese Medicine(The Second Affiliated Hospital of Henan University of Chinese Medicine)0 个研究点开始时间: 待定最近更新:
适应症

试验速览

阶段
1 期
状态
招募中
发起方

研究概览

简要总结

暂无简介。

研究设计

研究类型
Treatment study

入排标准

年龄范围
25 至 35(—)
性别
Male

入选标准

  • ?In line with the 2015 Chinese expert consensus on the diagnosis and treatment of varicocele [1], and one of the following conditions;
  • ?infertility;abnormal semen quality;The woman has normal fertility, or has a related disease that causes infertility but may be cured;
  • ?Abnormal semen quality is found by examination,although there is no requirement for fertility;
  • ?The related symptoms associated with varicocele (such as perineal or testicular bulging pain, etc.) are more serious and significantly affect the quality of life,and the conservative treatment does not improve significantly
  • ?The serum testosterone level of grade ? or ? varicocele decreased significantly excluding other diseases
  • References[1]:Chun-Hua Deng,Xue-Jun Shang.Chinese expert consensus on the diagnosis and treatment of varicocele.Zhonghua Nan Ke Xue.2015;21(11):1035-42.

排除标准

  • ?Secondary varicocele, including left renal vein nutcracker syndrome, abdominal and retroperitoneal tumor compression and other causes;
  • ?Combined with severe liver and kidney insufficiency, hypertension, diabetes, abnormal coagulation function, etc;
  • ?Combined with previous history of spermatic vein surgery and postoperative recurrence;
  • ?Combined with Azoospermia
  • ?Combined with congenital developmental abnormalities, genetic or psychiatric disorders, neurological disorders;
  • ?Combined with retrograde ejaculation, erectile dysfunction, testicular atrophy.

研究者

发起方
Henan Province Hospital of Traditional Chinese Medicine(The Second Affiliated Hospital of Henan University of Chinese Medicine)

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