The Effect of Beans Compared to Beef on Satiety and Food Intake in Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 2
- 主要终点
- Subjective appetite sensations
研究概览
简要总结
This human clinical trial is using a randomized crossover design to examine the effect of two varieties of beans compared to beef on satiety and food intake in older adults.
详细描述
This human clinical trial is using a randomized crossover design that includes 3 study visits separated by washout periods of at least 1 week. Each study visit will last approximately 4 hours and will occur at the Human Nutraceutical Research Unit (HNRU) at the University of Guelph. Study visits will occur in the morning and begin with measurement of fasting body weight. Participants will then complete a baseline satiety questionnaire before they consume a breakfast test meal (that includes either red kidney beans, black beans or extra-lean ground beef). After the breakfast meal, participants will complete a palatability questionnaire. They will also complete more satiety questionnaires at 15, 30, 45, 60, 120, 150 and 180 minutes. After 180 minutes, participants will be consume an ad libitum pizza lunch meal until they are comfortably full. Participants will then be sent home with a food scale and instructions to record everything they eat and drink for the remainder of the day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy males and females
- •≥60 years old
- •BMI between 18.5-30 kg/m2
排除标准
- •Medication use that is not at a stable dose (at least 3 months)
- •Natural health product use that is not at a stable dose (at least 3 months)
- •Antibiotic use in the past 3 months
- •Overnight shift work
- •Alcohol consumption >14 drinks/week or >4 drinks/sitting
- •Anaphylactic food allergy
- •Pulse (beans, lentils, chickpeas, dried peas) consumption >4 servings per week
- •Recent or intended significant weight loss or weight gain (>4 kg in previous 3 months)
- •Breakfast skipping ≥4 days per week
- •Vegan diet
- •Dislike or unable to consume beans, ground beef, shredded cheddar cheese, white tortilla wraps or frozen cheese pizza
- •Three Factor Eating Questionnaire scale scores >11 for Cognitive Restraint, >9 for Disinhibition, and >8 for Hunger
- •Diagnosed hypertension (blood pressure >140/90mmHg) that is not managed
- •Diagnosed digestive-related condition (i.e. Celiac Disease, constipation, gastritis, gastroesophageal reflux disease, gluten intolerance, hemorrhoids, inflammatory bowel disease (Crohn's, Ulcerative Colitis), irritable bowel syndrome, lactose intolerance)
- •Diagnosed cognitive-related condition (i.e. Alzheimer's Disease, amnesia, dementia, generalized anxiety disorder, major depressive disorder, Parkinson's Disease, schizophrenia, traumatic brain injury)
- •Medical condition that does not have stable management for at least 3 months
- •Medical or surgical event requiring hospitalization in the past 3 months
- •Tobacco use
- •Cannabis use
结局指标
主要结局
Subjective appetite sensations
时间窗: Area under the 180 minute curve
Fullness, satisfaction, hunger, desire to eat, prospective food consumption (measured by a visual analogue scale in mm)
次要结局
- Food intake at an ad libitum pizza meal(180 minutes after consumption of study treatment (in a breakfast meal))
- 24-hour energy intake(24 hours)
研究者
Alison Duncan
Professor
University of Guelph