The Effect of Psyllium Fiber Supplementation on Diarrhea in the Enteral-Tube Fed Patients: A prospective, Randomized, and Controlled Trial

Phase 3

Recruiting

• Conditions: Diarrhea; Tube feeding; Fiber; Hospitalized patients who receive enteral nutrition via tube feeding (nasogastric tube or orogastric tube); Psyllium; Nosocomial diarrhea; Enteral Nutrition; Blendera

• Registration Number: TCTR20170821004
• Lead Sponsor: Faculty of Medicine, Prince of Songkla University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-21
• Study Completion: 2017-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

-Patients at least 18 years of age
-Receiving enteral nutrition via tube feeding (nasogastric tube or orogastric tube)
-Expected to receive enteral feeding of at least 5 days

Exclusion Criteria

-Refuse to participate in the study
-Hemodynamic instability at the time of enteral tube feeding initiation (a mean arterial pressure (MAP) value less than 50 mmHg, or escalating doses of vasopressor/inotropic agent(s) requirement to maintain a MAP value more than 50 mmHgwithin 24 hours)
-Impossibility to use the gastrointestinal tract (hemorrhage, obstruction, severe ileus)
-Recent acute pancreatitis (within 2 weeks) or Chronic pancreatitis
-Known diarrheal illness causes by pre-existing gastrointestinal pathology (e.g. ulcerative colitis, Crohn's disease, ischemic or infectious colitis)
-Enteric fistula
-Patients with restricted enteral fluid intake < 1,500 ml/day
-Pregnancy
-Inability to distinguish between stool and urine during defecation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
proportion of patients with at least 1 day of diarrhea in enterally fed patients 10 days after start enteral feeding or death or discharge or change to oral diet KIng's stool chart

Secondary Outcome Measures

Name	Time	Method
percentage of days with diarrhea per total feeding days in enterally fed patients 10 days after start enteral feeding or death or discharge or change to oral diet KIng's stool chart