A novel approach for delivery of nasal topical corticosteroid sprays in post-surgery chronic rhinosinusitis

Not Applicable

• Conditions: post-surgery chronic rhinosinusitis; Functional endoscopic sinus surgery; Surgery - Other surgery; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12623000007639
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-01-09
• Last Update Posted: 16 January 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

Patients meeting the criteria of the 2020 European Position Paper (EPOS) definition of CRS patients with and without polyposis.
CRS patients that have undergone FESS

Exclusion Criteria

- Current malignant or significant cardiovascular disease
-Current smokers, i.e. those who had smoked within the last 12 months.
-Diabetes treated with insulin or other prescribed medications
-History of kidney disease as an adult, including renal tumour or transplant
-History of chronic lung diseases
-History of recurrent lung infections
-History of severe hepatic disease/liver transplant/pending liver transplant.
-History of severe or multiple allergies, including hay-fever and perennial rhinitis
-Hypertension (high blood pressure) requiring medication
-Multiple myeloma
-Participants with documented or suspected, clinically significant alcohol or drug abuse
-Pregnant
-Significant upper and/or lower respiratory tract infection within the previous 4 weeks
-Solid organ transplant

Study & Design

• Study Type: Interventional
• Study Design: Not specified