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A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)

Not Applicable
Recruiting
Conditions
Stress Urinary Incontinence (SUI)
Registration Number
NCT06968741
Lead Sponsor
UroMems SAS
Brief Summary

Prospective, multicenter, single-arm study

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
Male
Target Recruitment
140
Inclusion Criteria
  • Male subjects aged ≥ 22 years old
  • Able to read, comprehend and willing to sign an informed consent form
  • Primary diagnosis of stress urinary incontinence for at least 6 months, as assessed by the investigator
  • Appropriate surgical candidate with no medical or mental condition that would interfere with study procedures or confound study outcomes as assessed by the investigator

Key

Exclusion Criteria
  • Currently enrolled or plans to enroll in another investigational device or clinical drug trial or has completed an investigational study (for urinary incontinence) in the past 3 months prior to informed consent
  • Poor candidate for surgical procedures and/or anesthesia, as determined by investigator
  • Currently implanted with an Active Implantable Medical Device (AIMD)
  • Symptoms or diagnosis of urge incontinence or mixed incontinence (MI) with a predominant urgency component, as assessed by the investigator

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Responder rate at 26 weeks post-activation26 weeks

Proportion of subjects who report greater than or equal to 50% reduction in the 24 hour Pad Weight Test (PWT) at 26 weeks compared with Baseline

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Groupe Hospitalier Pitié-Salpêtrière

🇫🇷

Paris, France

Groupe Hospitalier Pitié-Salpêtrière
🇫🇷Paris, France
Emmanuel Chartier-Kastler
Contact
emmanuel.chartier-kastler@aphp.fr

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