Early Detection of the Effect of Epidural Local Anesthetic by Temperature Change on the Big Toe
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- measurement of skin temperature change over big toe after epidural local anesthetic injection
研究概览
简要总结
Traditionally, placement of the epidural catheter is based on hand feel of passing through the ligamentum flavum as well as "loss of resistance" while injecting the air through the needle. However, both are subjective and not necessarily encountered consistently. Moreover, the onset of sensory block is usually slow, thus making confirmation of catheter position a tough task and may delay the turnover of the operating room. The only way to confirm the catheter position objectively without delaying surgery is to find a reliable indicator within minutes of local anesthetic injection. In this study, we try to use the change of temperature in the big toe as a surrogate indicator of correct epidural catheterization.
详细描述
Epidural anesthesia loading dose: 17ml 2% xylocaine + 2.3ml sodium bicarbonate + 2ml Rapifen (1088 mcg) + 0.1 mg epinephrine
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Body weight:50-90kg,
- •American Society of Anesthesiologists physical status classification I-II,
- •Under epidural anesthesia for surgery
排除标准
- •History of receiving lumbar surgery
- •Allergy to alfentanil ,xylocaine, bicarbonate
研究组 & 干预措施
epidural injection
epidural injection of 2% lidocaine 17 ml + 2 ml alfentanil (544 mcg x 2 = 1088 mcg) + 7% sodium bicarbonate 2.3 ml (1.9 mEq) + 0.1mg epinephrine (1:200000)
干预措施: epidural injection (Drug)
结局指标
主要结局
measurement of skin temperature change over big toe after epidural local anesthetic injection
时间窗: within 10 mins after injection
SPECTRUM 9000MB to detect lower limb color changes
次要结局
- measurement of skin sensation change between inguinal area to umbilicus(within 15 mins after injection)