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Effect of Estrogen Dose in Endometrial Preparation for Frozen-Thawed Embryo Transfer on Endometrial Receptivity: A Double-blind, Randomized Clinical Trial

Not Applicable
Recruiting
Conditions
Endometrial receptivityEndometrial thickness
Endometrial receptivity
Endometrial thickness
Registration Number
TCTR20180718003
Lead Sponsor
/A
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
50
Inclusion Criteria

1.Infertility
2.Age 18-45 yr
3.FSH, LH, Estradiol day 3 in normal physiological range
4.Normal cycle length in previous 3 cycle
5.Willing to participate in the study

Exclusion Criteria

1.Contraindication to estrogen
2.Endometrial lesion such as polyp or synechiae
3.Previous use of drugs affecting the metabolism of estrogen such as Phenytoin, Rifampicin in previous 3 onths

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Endometrial receptivity Day 19-21 of menstrual cycle Immunohistochemistry
Secondary Outcome Measures
NameTimeMethod
Endometrial thickness Day 12-14 of menstrual cycle Ultrasound,Estradiol and Progesterone level Day 12-14 and 19-21 of menstrual cycle Blood sampling
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