High Flow Nasal Cannula Treatment for Viral Bronchiolitis in Infants, a Randomised Controlled Trial

Not Applicable

Active, not recruiting

• Conditions: Viral bronchiolitis; Respiratory - Other respiratory disorders / diseases; Infection - Other infectious diseases

• Registration Number: ACTRN12613000388718
• Lead Sponsor: Andreas Schibler

Brief Summary

Our randomized controlled trial in infants with bronchiolitis treated outside of an intensive care setting demonstrated a significantly lower escalation of care and treatment failure rate when high-flow was used early during the hospital admission as compared to standard-oxygen therapy.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-04-10
• Last Update Posted: 10 March 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 1472

Inclusion Criteria

Inclusion criteria are infants with a clinical diagnosis of bronchiolitis less than 12 months corrected age (greater than or equal to 37 weeks post-conceptional age) with an oxygen requirement in room air of SpO2 < 92% for tertiary centres and <94% for regional and metropolitan centres.

Exclusion Criteria

craniofacial malformation
impending intubation

Study & Design

• Study Type: Interventional
• Study Design: Not specified