A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF BHAVAPRAKASHOKTA SHEPHALIKA PATRA KASHAYAM AND RASNA GUGGULU IN GRIDHRASI W.S.R. TO SCIATICA
Trial Snapshot
- Phase
- Phase 3
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- improvement in subjective parameters like Ruk Stambh Tod Muhuspandana Graha Aruchi Tandra Gaurava
Study Overview
Brief Summary
The present clinical study entitled A Comparative Clinical Study to Evaluate the Efficacy of Bhavaprakashokta Shephalika Patra Kashayam and Rasna Guggulu in Gridhrasi w.s.r. to Sciatica aims to evaluate and compare the therapeutic effects of two classical Ayurvedic formulations in the management of Gridhrasi, a Vatavyadhi closely correlated with sciatica.
Gridhrasi is characterized by Ruka Stambha Toda Muhuspandanaand Sakthikshepa Nigrahaoften accompanied by Tandra, Gaurava, and Arochaka in Kaphanubandha type. The condition corresponds to the modern entity “sciatica,” involving radiating pain along the sciatic nerve due to compression or irritation.
The study is designed as a prospective, open-labelled, randomized clinical trial conducted on 40 patients, divided into two groups of 20 each.
Group A Shephalika Patra Kashayam 50 ml twice daily before meals
Group BRasna Guggulu 250 mg twice daily after meals
The treatment duration is 30 days, with a follow-up of 15 days, and both groups receive Ushna Jala as Anupana.
Both formulations are selected for their Vata-Kapha Shamak, Vedanasthapana, Amapachaka, and Shothahara properties.
Shephalika Patra Kashayam *Vitex negundo Linn.*possesses Ushna Veerya and Katu Vipaka, aiding in pain and inflammation reduction and Amapachana.
Rasna Guggulu combines Rasna Pluchea lanceolataand Guggulu Commiphora mukul providing potent Vatashamaka, anti-inflammatory, and analgesic actions.
This study seeks to establish a comparative evaluation of these two Ayurvedic regimens to determine which provides better relief in terms of pain, stiffness, and functional improvement, thereby offering an effective, safe, and economical alternative for the management of Gridhrasi
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Masking
- None
Eligibility Criteria
- Ages
- 16.00 Year(s) to 70.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •1.Patients aged between 16 to 70 years of any gender 2.Patients having clinical signs and symptoms of Gridhrasi 3.Patients willing to sign the informed consent form
- •SLR (Straitght Leg Raising) Test positive.
Exclusion Criteria
- •Pregnancy & Lactating women
- •Tuberculosis of spine
- •Diabetes mellitus
- •Cardiac Disease
- •Congenital Disease
- •Traumatic injury.
Outcomes
Primary Outcomes
improvement in subjective parameters like Ruk Stambh Tod Muhuspandana Graha Aruchi Tandra Gaurava
Time Frame: on 0 days to 30 days
Secondary Outcomes
- improvement in subjective parameters like Ruk Stambh Tod Muhuspandana Graha Aruchi(on 0 days to 30 days)
Investigators
Dr Jitendra Patel
Govt ayurveda college nipaniya rewa mp