A pilot study of psychotherapeutic intervention for complex presentations of first-episode psychosis

Recruiting

• Conditions: Borderline Personality Disorder; Early psychosis; Mental Health - Psychosis and personality disorders

• Registration Number: ACTRN12605000594628
• Lead Sponsor: Orygen Research Centre and Orygen Youth Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2005-10-05
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

(1) Eligibility for EPPIC program, 1 week or more of psychotic symptoms with less than 6 months of active previous treatment (i.e., antipsychotic medication); and (2) Diagnosis of four or more DSM-IV BPD traits (APA, 1994).

Exclusion Criteria

(1) Severe and enduring psychotic symptoms, defined as scores of 4 or more on 1 or more psychotic items of the Brief Psychiatric Rating Scale (BPRS) which have persisted for more than 1 month (Overall & Gorham, 1962); (2)Unable to converse in, or read English without an interpreter; (3) Intellectual deficits, such that unable to meaningfully participate in the psychotherapy; and (4) Already given informed consent for another psychotherapy trial at ORYGEN Youth Health, or already received a course of CAT.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
a) to refine an appropriate form of CAT for this group of patients and to produce a treatment manual directly at the end of the study[Outcomes (b) and (c) will be completed at the end of the treatment phase (for both conditions), and six months after the treatment phase.];b) to check the validity of outcome measures[Outcomes (b) and (c) will be completed at the end of the treatment phase (for both conditions), and six months after the treatment phase.];c) to explore effects in relation to psychopathology, psychosocial functioning, and quality of life over a 6-month follow-up period, with a view to conducting a larger randomized trial. [Outcomes (b) and (c) will be completed at the end of the treatment phase (for both conditions), and six months after the treatment phase.]

Secondary Outcome Measures

Name	Time	Method
To evaluate the safety of CAT for this group.[Safety will be measured at both the end of the treatment phase (for both conditions) and six months after the completion of the treatment phase.];To evaluate the feasibility of CAT for this group.[Feasibility will be measured at the end of the treatment phase.]