Evaluation the effect of sucralfate 15% mouthwash for Prevention and treatment mouth sores induced by chemotherapy drugs

Phase 2

• Conditions: 5-fluorouracil induced oral mucositis.; Disease of oral cavity : stomatitis; k00-k14

• Registration Number: IRCT201107053014N4
• Lead Sponsor: Vice chancellor for research, Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Cancer patients between 18-70 years receiving 5-fluorouracil containing chemotherapy regimens.
Exclusion criteria: Sucralfate intolerance or inappropriate use of the mouth wash

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mouth sores. Timepoint: every 3 days. Method of measurement: Use of the WHO table and ruler.

Secondary Outcome Measures

Name	Time	Method
Pain. Timepoint: Before and after 1 months of intervention. Method of measurement: Visual analoug scale (VAS).;Dysphagia to liquids. Timepoint: Before and after 2 months of intervention. Method of measurement: Ask a question.;Dysphagia to solids. Timepoint: weekly. Method of measurement: Ask a question.;Bleeding. Timepoint: Before and after 2 months of intervention. Method of measurement: Ask a question.