Biomarkers of the Response to Osteopathic Manipulation

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Osteopathic Manipulation; Other: Placebo

• Registration Number: NCT00958646
• Lead Sponsor: West Virginia School of Osteopathic Medicine

Brief Summary

The purpose of this study is to identify non-invasive biomarkers of the physiologic response to Osteopathic Manipulative Treatment (OMT).

Detailed Description

Not available

Study Timeline

• Study Start: 2009-08
• Study First Submitted: 2009-08-12
• Study First Submitted QC: 2009-08-12
• Study First Posted: 2009-08-13
• Primary Completion: 2010-08
• Study Completion: 2010-12
• Status Verified: 2011-07
• Last Update Submitted: 2011-07-12
• Last Update Posted: 2011-07-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• Healthy adults between the ages of 21 and 60

Exclusion Criteria

• Eating or drinking anything but water or chewing gum within an hour of the appointment
• Rib fracture
• History of unstable cardiac arrhythmia or symptoms related to the chest cavity (difficulty breathing, chest pain)
• Symptoms suggestive of bowel obstruction (abdominal bloating with pain, nausea and vomiting, diarrhea)
• Pregnancy
• History of Sjogren's Syndrome

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Osteopathic Manipulation	Osteopathic Manipulation	Standardized OMT procedure
Placebo	Placebo	Light touch placebo procedure

Primary Outcome Measures

Name	Time	Method
Salivary amylase levels	baseline, 10 minutes post procedure

Trial Locations

Locations (1)

West Virginia School of Osteopathic Medicine; 🇺🇸 Lewisburg, West Virginia, United States