Investigation of Peripheral Muscle Oxygenation At Rest and Movement in Hospitalized Patients in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Comparison with Stable Period
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Obstructive Pulmonary Disease
- Sponsor
- Bandırma Onyedi Eylül University
- Enrollment
- 41
- Locations
- 1
- Primary Endpoint
- Muscle oxygenation
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
The aim of our study is to examine the Peripheral Muscle Oxygenations at rest and in motion on the 2nd day of hospitalized patients and before discharge in Severe Acute Exacerbation of Chronic Obstructive Pulmonary Disease and to compare the results in the hospital periods by repeating the tests in the stable periods of the patients 1 month after discharge.
Investigators
Gulhan Yilmaz Gokmen
Assistant Professor
Bandırma Onyedi Eylül University
Eligibility Criteria
Inclusion Criteria
- •Being a COPD patient hospitalized with Severe Acute Exacerbation
- •be between 40-80 years old
- •Having a Body Mass Index below 35
Exclusion Criteria
- •Patients who do not want to participate in the study
- •Patients requiring intensive care follow-up during their hospitalization Arthritis, neurological disease, deep vein thrombosis, peripheral arterial disease, muscle weakness, broken etc. patients with the condition
- •Extensive parenchyma such as malignancy, pulmonary embolism, vasculitis, collagen tissue diseases, interstitial fibrosis, severe pneumonia patients with damage
- •Patients with severe dyspnea and hemodynamic instability who cannot perform the sit-up test
Outcomes
Primary Outcomes
Muscle oxygenation
Time Frame: 4 weeks
The muscle oxygen monitor is a lightweight (42 g) and small (dimensions: 61 × 44 × 21 mm) device that measures regional blood flow and oxygenation by placing it on the skin non-invasively with near infrared spectroscopy (NIRS). The device, which has data collection and telemetric features, also allows O 2 measurement in non-laboratory environments and field-based research.
Secondary Outcomes
- COPD Assessment Test (CAT)(4 weeks)
- Modified Medical Research Council Dyspnea Scale:(4 weeks)
- 1 minute sit and stand test(4 weeks)
- Charlson Comorbidity Index(4 weeks)