The Role of Synbiotic in the Treatment of Childhood Constipatio
Phase 1
- Conditions
- Other diseases of intestines.Constipation
- Registration Number
- IRCT138811193309N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Age 4-12 years, diagnosis based on Room III criteria as two months of at least 2 or more of the following: less than 2 defecation in the toilet per week, more than 1 episode of fecal incontinence per week, history of retentive posturing or excessive volitional stool retention, history of painful or hard bowel movements, presence of a large fecal mass in the rectum, history of large diameter stools that may obstruct the toilet.
Exclusion criteria: presence of organic causes for constipation; including Hirschsprung’s disease, spina bifida occulta, hypothyroidism, cystic fibrosis, neurologic abnormalities and intestinal pseudo-obstruction
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of bowel movements per week. Timepoint: 4 weeks. Method of measurement: Questionnarie.;Stool consistency. Timepoint: 4 Weeks. Method of measurement: Questionnarie.;Frequency of stool incontinence per week. Timepoint: 4 Weeks. Method of measurement: questionnarie.;Abdominal pain. Timepoint: 4 weeks. Method of measurement: questionnarie.;Painful defecation. Timepoint: 4 weeks. Method of measurement: Questionnarie.
- Secondary Outcome Measures
Name Time Method Success treatment. Timepoint: 4 weeks. Method of measurement: Success treatment defined as = 3 Bowel Movements per week,= 2 incontinence per month and no abdominal pain.;Adverse effects. Timepoint: 4 weeks. Method of measurement: Questionnarie.