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Clinical Trials/NCT04067687
NCT04067687
Completed
N/A

Palliative Intervention to Improve Quality of Life in Children With Cancer: A Randomized Controlled Trial

Indonesia University1 site in 1 country60 target enrollmentJanuary 1, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pediatric Cancer
Sponsor
Indonesia University
Enrollment
60
Locations
1
Primary Endpoint
Quality of life cancer child
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

A randomized controlled trial to compare the quality of life between participants who were given palliative care (a 3-month home visit) and those who were not (intervention vs control group) was conducted. Participants consisted of children with cancer aged 2-18 years old. A two-way communication between a trained health worker and participants with or without their parents were conducted as the intervention (report by proxy or self-report). Interventions were given in 6 sessions (1 session every 2 weeks) focusing on problems solving education, symptoms management, self-care, communication, decision making, and long-term care plan assistance. In the first and twelfth week of the intervention, all participants were assessed with the Pediatric Quality of Life Inventory (PedsQLTM) questionnaire cancer module 3.0. Symptomps intensityof anorexia, sleep diturbance, and pain will be asessed in each visit. Participants were followed, Emergency Room (ER) admissions were recorded during follow up period. During the follow up period, ER admissions were recorded further.

Registry
clinicaltrials.gov
Start Date
January 1, 2019
End Date
September 30, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Murti Andriastuti, Doctor

Principal Investigator

Indonesia University

Eligibility Criteria

Inclusion Criteria

  • Child age 2-18 years old with malignancies who undergo treatments at the Department of Child Health of Cipto Mangunkusumo Hospital, during the study period.
  • All participants who meet the criteria to get palliative care, participants with a total score ≥ 4 based on palliative screening form.
  • Participants and or parents agree to be enrolled in study

Exclusion Criteria

  • Patients who live outside Jakarta and therefore unreachable to get palliative intervention

Outcomes

Primary Outcomes

Quality of life cancer child

Time Frame: at the end of 3 months follow up

Measured using PedsQLTM cancer module 3.0 that consisted of eight dimension. Each dimension consisted of several items to be answered. Item scaling was answered in 5-point Likert scale from 0 (Never) to 4 (Almost always). Scores are transformed to a 0 to 100 scale. Items are reversed scored and linearly transformed to a 0-100 scale as follows: 0=100, 1=75, 2=50, 3=25, 4=0. If more than 50% of the items in the scale are missing, the scale scores should not be computed. Mean score = Sum of the items over the number of items answered. Total score is acquired by summing of all the items over the number of items answered on all the Scales.Higher scores indicate lower problems.

Secondary Outcomes

  • Emergency room visits(during 3 months follow up)
  • Symptomps intensity(during 3 months follow up)

Study Sites (1)

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