Acute Right Ventricular Infarction Registry

Recruiting

• Conditions: Inferior Wall; Transmural Myocardial Infarction; Right Ventricular Dysfunction

• Registration Number: NCT06424028
• Lead Sponsor: National Institute of Cardiovascular Diseases, Pakistan

Brief Summary

This Study aims to provide an assessment of clinical presentation, management, hospital course, and prognosis of acute right ventricular infarction presenting with or without Inferior or infero-posterior wall Myocardial Infarction and the assessment of composite adverse clinical outcome after reperfusion in-hospital and post-discharge (in 30 Days Prognosis).

Detailed Description

After fulfilling the eligibility criteria, informed consent will be obtained from all the patients regarding using data for research while maintaining anonymity.Data will be collected for various patient, system, and procedure related characteristics with the help of a predefined structured proforma consisted of demographic data, clinical presentation, history and co-morbid conditions, and angiographic and procedural characteristics. All the recruited patients will be kept under observiton during the hospital stay and a telephonic follow-up will be carried out after 30-days of discharge and occurrence of the MACE will be recorded.

Univariate and multivariable binary logistic regression analysis will be performed to determine the clinical predictors of RVI. Odds ratio (OR) along with 95% confidence interval (CI) will be reported. The statistical significance criteria will be set as p-value\<0.05.

For data verification, 10% of the data will be cross-checked with the source document (Patient file).

Study Timeline

• Study Start: 2024-01-20
• Status Verified: 2024-05
• Study First Submitted: 2024-05-10
• Study First Submitted QC: 2024-05-15
• Last Update Submitted: 2024-05-15
• Study First Posted: 2024-05-21
• Last Update Posted: 2024-05-21
• Primary Completion: 2024-07-19
• Study Completion: 2024-08-19

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Patients of Inferior, infero-lateral and infero-posterior wall MI with and without RV infarction undergoing PPCI.
• Both male and female patients.
• Patients of age ≥ 18 years.

Exclusion Criteria

• Patients who will not give consent for participation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Composite adverse clinical outcome	Upto 30 days from admission	Atleast one adverse event, such as pump failure, cerebrovascular accident (CVA), stent thrombosis, major bleeding, contrast-induced nephropathy (CIN), ventricular arrhythmias, or mortality.

Trial Locations

Locations (1)

National Institute of Cardiovascular Diseases; 🇵🇰 Karachi, Sindh, Pakistan