Evaluation of T2, T3 Sympathectomy for Postmastectomy Pain Syndrome by Pulse Oximeter

Not Applicable

Completed

• Conditions: Analgesia

• Registration Number: NCT04953507
• Lead Sponsor: National Cancer Institute, Egypt

Brief Summary

The aim of the study is to compare the efficacy of T2, T3 sympathetic block using thermal radiofrequency versus chemical neurolysis in postmastectomy pain syndrome using perfusion index derived from pulse oximetry.

Detailed Description

Postmastectomy pain is a chronic pain condition with neuropathic nature. Several drugs and methods are used for its management. This study was designed to compare the efficacy of both thermal radiofrequency and chemical neurolysis in management of postmastectomy pain through using perfusion index derived from pulse oximetry.

Study Timeline

• Study First Submitted: 2021-06-28
• Study Start: 2021-07-03
• Study First Submitted QC: 2021-07-06
• Study First Posted: 2021-07-08
• Primary Completion: 2025-02-10
• Study Completion: 2025-02-25
• Status Verified: 2025-07
• Last Update Submitted: 2025-07-16
• Last Update Posted: 2025-07-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 54

Inclusion Criteria

• Female patients with postmastectomy pain syndrome
• ≥ Age 18 years
• ASA II-III

Exclusion Criteria

• patient refusal
• coagulation defects
• abnormal kidney or liver functions
• local infection at site of injection
• bone metastases
• severe cardiorespiratory disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Visual analogue score	up to 24 weeks	minimum score 0 and maximum score 10

Secondary Outcome Measures

Name	Time	Method
Perfusion index trend	procedure time	measuring the change in perfusion index in the ipsilateral limb after the procedure compared to pre-procedural
Opioid consumption	up to 24 weeks	average opioid consumption

Trial Locations

Locations (1)

Walaa Y Elsabeeny; 🇪🇬 Cairo, Egypt